Mark Roth is a biomedical scientist whose pioneering research ranges from molecular mechanisms of genetic regulation to whole-animal physiology to medical diagnostics. In his early work on messenger RNA processing, he discovered a class of molecules known as SR proteins, which play a key role in stabilizing mRNA as it undergoes the post-transcriptional maturation process. Mark Roth received a B.Sc. (1979) from the University of Oregon and a Ph.D. (1984) from the University of Colorado at Boulder. Since 1989, he has been a member of the Fred Hutchinson Cancer Research Center’s Basic Sciences Division. He is also an affiliate associate professor in the Department of Biochemistry at the University of Washington in Seattle.