Keller Brown is a co-founder of Pelopidas, an influence management firm, and president of Keller Capital Group, a fundraising and political consulting firm. As chief of staff for Sinquefield, she advises him on political and philanthropic giving programs, manages issue advocacy regarding education reform and tax policy and oversees daily operations and special projects. She also serves on the board of the Missouri History Museum. Keller Brown is the board president of the Children’s Education Alliance of Missouri and vice chair of the St. Vincent Home for Children. She sits on the boards of the Regional Arts Commission, the Missouri History Museum, Opera Theatre Saint Louis, the Loop Trolley, Covenant House, the National Children's Cancer Society, and the Today and Tomorrow Educational Foundation, which provides needs-based scholarships to children throughout the Archdiocese of St. Louis. Additionally, she serves on the advisory committee of the Innovative Concept Academy and the executive committee of STL 250. Keller Brown recently became a member of the St. Louis Civic Pride Foundation.